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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA4
All Species:
25.45
Human Site:
S634
Identified Species:
46.67
UniProt:
P13612
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13612
NP_000876.3
1032
114872
S634
C
S
A
D
L
Q
V
S
A
K
I
G
F
L
K
Chimpanzee
Pan troglodytes
XP_525977
1032
114817
S634
C
S
A
D
L
Q
V
S
A
K
I
G
F
L
K
Rhesus Macaque
Macaca mulatta
XP_001100929
1032
114958
S634
C
S
A
D
L
Q
V
S
A
K
I
G
F
F
K
Dog
Lupus familis
XP_545551
1165
128321
S769
C
S
A
D
L
Q
V
S
A
R
I
G
F
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q00651
1039
115677
S641
C
S
A
D
L
Q
V
S
A
K
V
G
F
L
K
Rat
Rattus norvegicus
Q63258
1135
124176
D671
Q
A
L
P
M
D
L
D
G
T
A
L
F
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515892
940
104353
Y569
L
M
L
N
V
S
L
Y
N
A
G
D
D
A
F
Chicken
Gallus gallus
P26008
1034
114370
C618
D
C
G
E
D
N
I
C
K
P
K
L
E
V
S
Frog
Xenopus laevis
Q91687
1032
115197
T634
C
S
A
D
L
Q
I
T
G
K
R
S
F
P
K
Zebra Danio
Brachydanio rerio
XP_002663459
1018
113210
S624
C
S
T
N
L
Q
V
S
A
R
L
V
L
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24247
1146
127955
I652
L
C
E
S
N
L
I
I
R
V
E
P
N
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34446
1226
135921
V653
C
G
K
D
D
L
C
V
P
D
L
K
V
T
A
Sea Urchin
Strong. purpuratus
XP_794080
1226
134761
K815
V
N
I
T
I
P
W
K
T
K
N
G
D
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
75.1
N.A.
84.1
25.8
N.A.
65.5
26.2
54.4
47.6
N.A.
24
N.A.
22.1
24.7
Protein Similarity:
100
99.9
98.4
81.7
N.A.
91.8
44.4
N.A.
77.5
46.6
74.1
65.3
N.A.
43.4
N.A.
41.3
42.9
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
6.6
N.A.
0
0
60
46.6
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
26.6
N.A.
20
20
73.3
73.3
N.A.
13.3
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
0
0
0
0
0
47
8
8
0
0
16
8
% A
% Cys:
62
16
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
54
16
8
0
8
0
8
0
8
16
0
0
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
54
8
8
% F
% Gly:
0
8
8
0
0
0
0
0
16
0
8
47
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
24
8
0
0
31
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
8
8
47
8
8
0
0
47
% K
% Leu:
16
0
16
0
54
16
16
0
0
0
16
16
8
31
16
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
16
8
8
0
0
8
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
8
8
0
8
0
16
0
% P
% Gln:
8
0
0
0
0
54
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
16
8
0
0
0
0
% R
% Ser:
0
54
0
8
0
8
0
47
0
0
0
8
0
0
8
% S
% Thr:
0
0
8
8
0
0
0
8
8
8
0
0
0
8
8
% T
% Val:
8
0
0
0
8
0
47
8
0
8
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _